FIGURE

Fig. 3

ID

ZDB-FIG-140613-11

Publication

Myhre et al., 2014 - Unc45b is essential for early myofibrillogenesis and costamere formation in zebrafish

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Fig. 3

unc45b mRNA expression correlates to non-muscle myosin but not muscle myosin in paraxial mesoderm. In situ hybridization, high magnification view of developing somites in zebrafish embryos at the 2-somite, (A, D, G, J), 5-somite (B, E, H, K) and 10-somite (C, F, I, L) stages. Non-muscle myosin (myh10, A–C) and unc45b (D–F) were expressed consistently in both adaxial cells (arrows) and lateral paraxial mesoderm (arrowheads) at all stages. In contrast, slow-muscle myosin (smyhc1, G–I) was expressed only in adaxial cells (arrows) at these stages, beginning lateral migration into the somites only at the latest stages examined (white arrowhead in I). Fast-muscle specific myosin (myhc4, J–L) was expressed after the 5-somite stage, and only in adaxial cells (arrows).

Expression Data

Genes:	myh10 myhc4 smyhc1 unc45b
Fish:	AB
Anatomical Terms:	adaxial cell paraxial mesoderm
Stage Range:	1-4 somites to 10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 390, Myhre, J.L., Hills, J.A., Jean, F., Pilgrim, D.B., Unc45b is essential for early myofibrillogenesis and costamere formation in zebrafish, 26-40, Copyright (2014) with permission from Elsevier. Full text @ Dev. Biol.