FIGURE

Fig. 6

ID

ZDB-FIG-140226-49

Publication

Griffin et al., 1995 - Analysis of FGF function in normal and no tail zebrafish embryos reveals separate mechanisms for formation of the trunk and the tail

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Fig. 6

FGF-dependent regulation of eve1 and cad1 expression. (A-C) Animal pole views of eve1 expression at the shield stage. In a normal embryo (A) eve1 is only expressed in the ventral and lateral germ ring. (B) This embryo has been injected with the dominant negative FGFR and no eve1 expression can be detected. (C) An embryo injected with eFGF RNA and showing ubiquitous expression of eve1. (D-F) Lateral views of cad1 expression during early gastrulation. (D) Normal embryo at 65% epiboly showing strong cad1 expression throughout the germ ring. (E) Embryo injected with dominant negative FGFR RNA, with a clear gap (arrowhead) in cad1 expression. (F) Embryo injected with eFGF RNA; cad1 is expressed ubiquitously. (G,H) Lateral views of cad1 expression at 18 hpf. (G) Normal embryo, anterior to the right, with yolk cell dissected away. cad1 is only expressed in the tail region, especially in the tail bud (arrowhead). (H) Injected embryo showing that ubiquitous expression of cad1 persists to this stage.

Expression Data

Genes:	cdx4 eve1
Fish:	WT
Anatomical Terms:	germ ring germ ring ventro-lateral region
Stage:	Shield

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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