FIGURE

Fig. S4

ID

ZDB-FIG-131010-14

Publication

D'Aniello et al., 2013 - Depletion of Retinoic Acid Receptors Initiates a Novel Positive Feedback Mechanism that Promotes Teratogenic Increases in Retinoic Acid

Other Figures

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Fig. S4

Specificity controls for the translation blocking rarαb1 MO. (A–C) Control sibling, RARαb1 deficient, and RARαb1 deficient+rarαb1 mRNA injected embryos. Images are lateral views with anterior right at 48 hpf. Red outline indicates ventricles. Green outline indicates atria. Arrow in B indicates edema often found in RARαb1 deficient embryos, which is not found in RARαb1 deficient+rarαb1 mRNA injected embryos (C). (D) qPCR for CM differentiation marker genes at 48 hpf in control sibling, RARαb1 deficient, RARαb1 deficient embryos+rarαb1 mRNA, and RARαb1 deficient embryos+kaede (control) mRNA injected embryos at 48 hpf. Pound sign indicates a statistically significant difference compared to RARαb1 deficient and RARαb1 deficient embryos+kaede (control) mRNA injected embryos (p<0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.