FIGURE

Fig. 4

ID

ZDB-FIG-130619-25

Publication

Nair et al., 2013 - The chromosomal passenger protein birc5b organizes microfilaments and germ plasm in the zebrafish embryo

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Fig. 4

Birc5b protein is expressed during meiosis, mitosis, and cytokinesis.

Birc5b is expressed along the length of the meiotic spindle during anaphase and concentrates at the spindle midzone (A–E). Birc5b localizes to the meiotic midbody and concentrates at one end, corresponding to the ooplasmic side (F–J, arrow in H, I). During mitotic metaphase Birc5b co-localizes with AurB on the spindle (K–O). During cytokinesis in the early embryo, Birc5b localizes to the tips of bundled microtubules at the furrow (P–R). At the midbody in the cleavage-stage embryo, shown here at 2 hpf (S–V), Birc5b expression (U) overlaps with AurB (T) at the center of bundled microtubules (S) and extends beyond it.

Expression Data

Genes:	aurkb birc5b
Antibodies:	Ab1-aurkb Ab2-birc5
Fish:	WT
Anatomical Terms:	blastomere equatorial microtubule organizing center blastomere mitotic spindle unfertilized egg meiotic spindle unfertilized egg spindle midzone
Stage:	1-cell

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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