ZFIN is now using GRCz12tu for Genomic Data
Gene
birc5b
- ID
- ZDB-GENE-030826-2
- Name
- baculoviral IAP repeat containing 5b
- Symbol
- birc5b Nomenclature History
- Previous Names
-
- survivin 2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable metal ion binding activity. Acts upstream of or within several processes, including circulatory system development; nuclear chromosome segregation; and regulation of apoptotic process. Predicted to be located in chromosome, centromeric region and spindle. Is expressed in several structures, including axial blood vessel; caudal vein plexus; intermediate cell mass of mesoderm; nervous system; and unfertilized egg. Human ortholog(s) of this gene implicated in prostate cancer and transitional cell carcinoma. Orthologous to human BIRC5 (baculoviral IAP repeat containing 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 16 figures from 4 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Baculoviral IAP repeat-containing | BIR repeat |
|---|---|---|---|---|
| UniProtKB:Q90WU8 | InterPro | 128 | ||
| UniProtKB:A0A8M9PSV1 | InterPro | 102 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
birc5b-201
(1)
|
Ensembl | 598 nt | ||
| ncRNA |
birc5b-002
(1)
|
Ensembl | 612 nt | ||
| ncRNA |
birc5b-003
(1)
|
Ensembl | 525 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab2-birc5 | monoclonal | IgG | Rabbit |
|
Cell Signaling Technology, Inc.
|
3 |
Plasmids
No data available
- Genome Browsers