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General Information
ZIRC
ZFIN ID: ZDB-FIG-130531-10
Wang et al., 2011 - A blood flow-dependent klf2a-NO signalling cascade is required for stabilization of hematopoietic stem cell programming in zebrafish embryos. Blood   118(15):4102-10 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage: Prim-25
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Prim-25

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
nos1 WT control Prim-25 trunk RTPCR
WT + MO1-klf2a standard conditions Prim-25 trunk RTPCR
nos2b WT control Prim-25 trunk RTPCR
WT + MO1-klf2a standard conditions Prim-25 trunk RTPCR
runx1 WT control Prim-25 hematopoietic multipotent progenitor cell ISH
Prim-25 trunk vasculature ISH
WT + MO1-klf2a chemical treatment: S-nitroso-N-acetyl-D-penicillamine Prim-25 hematopoietic multipotent progenitor cell ISH
Prim-25 trunk vasculature ISH
WT + MO1-klf2a standard conditions Prim-25 hematopoietic multipotent progenitor cell ISH
WT + MO1-tnnt2a chemical treatment: S-nitroso-N-acetyl-D-penicillamine Prim-25 hematopoietic multipotent progenitor cell ISH
Prim-25 trunk vasculature ISH
WT + MO1-tnnt2a standard conditions Prim-25 hematopoietic multipotent progenitor cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-klf2a chemical treatment: S-nitroso-N-acetyl-D-penicillamine Prim-25 hematopoietic multipotent progenitor cell normal amount, normal
WT + MO1-klf2a standard conditions Prim-25 hematopoietic multipotent progenitor cell decreased amount, abnormal
Prim-25 nitric oxide biosynthetic process disrupted, abnormal
WT + MO1-tnnt2a chemical treatment: S-nitroso-N-acetyl-D-penicillamine Prim-25 hematopoietic multipotent progenitor cell normal amount, normal
WT + MO1-tnnt2a standard conditions Prim-25 hematopoietic multipotent progenitor cell decreased amount, abnormal
Prim-25 nitric oxide biosynthetic process disrupted, abnormal
Full text @ Blood