Fig. s3
- ID
- ZDB-FIG-130128-11
- Publication
- Torregroza et al., 2012 - Regulation of a Vascular Plexus by gata4 Is Mediated in Zebrafish through the Chemokine sdf1a
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Modulation of Sdf1a is not sufficient to rescue the cardiac defect of gata4 morphants. A) Control uninjected embryos at 2 dpf have normal looped hearts, as visualized in the tg(myl7:gfp) transgenic reporter background. B) Hearts fail to loop in the gata4 morphant embryos. C) Likewise, the hearts fail to loop properly in gata4 morphants that are co-injected with the sdf1a morpholino. In the example shown here, 2 ng of sdf1a morhoplino was used, but we also failed to reproducibly rescue cardiogenesis with higher or lower doses. |