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ZFIN ID: ZDB-FIG-130109-8
Ichimura et al., 2012 - Structural disorganization of pronephric glomerulus in zebrafish mpp5a/nagie oko mutant. Developmental dynamics : an official publication of the American Association of Anatomists   241(12):1922-1932 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Observed In:
Stage Range: Long-pec to Day 4

Fig. 3 mpp5am520 mutant displays structural disorganization of pronephric glomerulus. Pronephric glomerular structure is shown by hematoxylin-eosin stained JB-4 section at 2 dpf (A-C), 3 dpf (D–F), and 4 dpf (G-I). In wild type siblings, a pair of glomerular primordia has merged to form a single glomerulus (arrowheads) beneath the notochord at 2 dpf (A), 3 dpf (D), and 4 dpf (G). In 2-dpf mpp5am520 mutants, a pair of glomerular primordia retains epithelial vesicular structure that does not merge beneath the notochord (arrows in B, C). At 3 and 4 dpf mpp5am520 mutants still exhibited two separated podocyte masses (arrows in E, F, H, I). Scale bar = 10 μm.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
pals1am520/m520 standard conditions Long-pec pronephric glomerulus disorganized, abnormal
Long-pec pronephric glomerulus unfused from pronephric glomerulus, abnormal
Long-pec pronephros development process quality, abnormal
Protruding-mouth pronephric glomerulus disorganized, abnormal
Protruding-mouth pronephric glomerulus unfused from pronephric glomerulus, abnormal
Protruding-mouth pronephros development process quality, abnormal
Day 4 pronephric glomerulus disorganized, abnormal
Day 4 pronephric glomerulus unfused from pronephric glomerulus, abnormal
Day 4 pronephros development process quality, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.