ZFIN ID: ZDB-FIG-130109-10
Ichimura et al., 2012 - Structural disorganization of pronephric glomerulus in zebrafish mpp5a/nagie oko mutant. Developmental dynamics : an official publication of the American Association of Anatomists   241(12):1922-1932 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage Range: Long-pec to Protruding-mouth
PHENOTYPE:
Fish:
Observed In:
Stage Range: Long-pec to Protruding-mouth

Fig. 5 nephrin mRNA expression in pronephric glomeruli of mpp5am520 mutant. Position and shape of pronephric glomerulus are shown by in situ hybridization for nephrin mRNA at 2 dpf (A, B) and 3 dpf (C-E), which only express in podocytes. nephrin mRNA is expressed in the glomerulus at 2 and 3 dpf in wild-type embryos as a single globular mass beneath the notochord (A, C; arrowheads). In the mpp5am520 mutant, the glomerulus (glomerular primordia) express nephrin mRNA in a domain shaped like a moustache at 2 and 3 dpf (arrows in B, D, E). Scale bar = 10 μm.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
nphs1 WT standard conditions Long-pec pronephric podocyte ISH
Protruding-mouth pronephric podocyte ISH
pals1am520/m520 standard conditions Long-pec pronephric podocyte ISH
Protruding-mouth pronephric podocyte ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
pals1am520/m520 standard conditions Long-pec pronephric podocyte nphs1 expression spatial pattern, abnormal
Protruding-mouth pronephric podocyte nphs1 expression spatial pattern, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.