FIGURE

Fig. 6

ID

ZDB-FIG-120628-1

Publication

Eauclaire et al., 2012 - Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

Changes in fibrogenic gene expression in pn. Quantitative real-time PCR on pn for hsp47 (A), vimentin (vime) (B), and collagen I(α)I (col1a1) (C). There is a significant decrease (pb0.03, pb0.05, pb0.01) for all the three genes. QPCR results for the other V-H⁺-ATPase gene mutants and morphants show minimal changes and are depicted in Supplemental Fig. 5.

Expression Data

Genes:	col1a1a serpinh1b vim
Fish:	WT atp6ap2^p250/p250 (AB/TU)
Anatomical Term:	whole organism
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 365(2), Eauclaire, S.F., Cui, S., Ma, L., Matous, J., Marlow, F.L., Gupta, T., Burgess, H.A., Abrams, E.W., Kapp, L.D., Granato, M., Mullins, M.C., and Matthews, R.P., Mutations in vacuolar H(+)-ATPase subunits lead to biliary developmental defects in zebrafish, 434-444, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.