Gene
vim
- ID
- ZDB-GENE-011212-3
- Name
- vimentin
- Symbol
- vim Nomenclature History
- Previous Names
-
- cb28 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be a structural constituent of cytoskeleton. Acts upstream of or within wound healing. Predicted to be active in several cellular components, including axon; intermediate filament; and plasma membrane. Is expressed in several structures, including axis; integument; midbrain neural keel; nervous system; and neural tube. Human ortholog(s) of this gene implicated in atherosclerosis; autoimmune disease (multiple); and cataract 30. Orthologous to human VIM (vimentin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 29 figures from 19 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb28 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from LeBert et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cataract 30 | Alliance | Cataract 30, pulverulent | 116300 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Intermediate filament head, DNA-binding domain | Intermediate filament protein, conserved site | Intermediate filament, rod domain | Intermediate filament structural protein |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M9PXB1 | InterPro | 417 | ||||
| UniProtKB:Q9YHX5 | InterPro | 455 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-vim | monoclonal | IgG1 | Mouse |
|
Sigma-Aldrich
Millipore Dako North America, Inc. Abcam plc Novus Biologicals, LLC Vector Laboratories |
14 |
Plasmids
No data available