Gene
vim
- ID
- ZDB-GENE-011212-3
- Name
- vimentin
- Symbol
- vim Nomenclature History
- Previous Names
-
- cb28 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Involved in wound healing. Predicted to localize to intermediate filament. Is expressed in several structures, including axis; integument; midbrain neural keel; nervous system; and neural tube. Human ortholog(s) of this gene implicated in atherosclerosis; autoimmune disease (multiple); and cataract 30. Orthologous to human VIM (vimentin).
- Genome Resources
- Note
- None
- All Expression Data
- 17 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
- cb28 (16 images)
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from LeBert et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
cataract 30 | Alliance | Cataract 30, pulverulent | 116300 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR018039 | Intermediate filament protein, conserved site |
Domain | IPR006821 | Intermediate filament head, DNA-binding domain |
Domain | IPR039008 | Intermediate filament, rod domain |
Family | IPR027699 | Vimentin |
Homologous_superfamily | IPR042180 | Intermediate filament, rod domain, coil 1B |
Domain Details Per Protein
Protein | Length | Intermediate filament head, DNA-binding domain | Intermediate filament protein, conserved site | Intermediate filament, rod domain | Intermediate filament, rod domain, coil 1B | Vimentin |
---|---|---|---|---|---|---|
UniProtKB:F1QAM8
|
455 | |||||
UniProtKB:Q9YHX5
|
455 |
Interactions and Pathways
No data available
Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
---|---|---|---|---|---|---|---|
Ab1-vim | monoclonal | IgG1 | Mouse |
|
Sigma-Aldrich
Millipore Dako North America, Inc. Abcam plc Novus Biologicals, LLC Vector Laboratories |
10 |
Plasmids
No data available
- Gene Tree
- Ensembl