FIGURE

Fig. S6

ID

ZDB-FIG-120202-56

Publication

Dohn et al., 2012 - Distinct phases of Wnt/β-catenin signaling direct cardiomyocyte formation in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Fig. S6

Modulation of Wnt signaling at the end of gastrulation has minimal effects on CP marker expression at 8 somites. (A,C,E,G) HCSEs. (B,F) GFP + embryos with decreased Wnt signaling at the TB stage. There is not a discernible difference in the expression of nkx2.5 (B) or gata4 (F) when these markers begin robust expression at 8 s. (D,H) GFP + embryos with increased Wnt signaling at the TB stage. (D) The majority of embryos with increased Wnt signaling at TB stage had nkx2.5 expression that was comparable to HCSEs. (H) There is not a discernible difference in the expression of gata4 at 8 s when Wnt signaling is increased at TB stage. (I,J) qPCR analysis of nkx2.5 and gata4 expression in embryos at the 8 s stage after modulating Wnt signaling at the TB stage. There is no difference in the expression levels of these CP marker genes relative to HCSEs.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image.

Reprinted from Developmental Biology, 361(2), Dohn, T.E., and Waxman, J.S., Distinct phases of Wnt/β-catenin signaling direct cardiomyocyte formation in zebrafish, 364-76, Copyright (2012) with permission from Elsevier. Full text @ Dev. Biol.