ZFIN ID: ZDB-GENE-980526-171
Gene Name: T-box 16, like
Gene Symbol: tbx16l
Sequence Ontology ID : SO:0000704

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Previous Names: tbx6, tbx6l, z.TBX6 (1), ZF-TBX6 (1), cb123 (1), etID309793.5 (1), sb:cb123

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have DNA binding activity and DNA-binding activity transcription factor activity; involved in paraxial mesoderm formation and somite development; predicted to localize to the nucleus;  ...
GENE EXPRESSION
All Expression Data: 72 figures from 52 publications
Directly Submitted Expression Data: 4 figures (4 images) from Thisse et al., 2001 [cb123]
Wild-type Stages, Structures: Blastula:Dome (4.33h-4.66h) to Pharyngula:Prim-15 (30.0h-36.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31470 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • z34 Small Deletion Unknown Frameshift, Premature Stop TALEN
    z35 Small Deletion Unknown Frameshift, Premature Stop TALEN
    Targeting reagents:
    PHENOTYPE
    Data: Fig. 4 from Morrow et al., 2017
    Observed in:
    DISEASE ASSOCIATED WITH tbx16l HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    spondylocostal dysostosis Spondylocostal dysostosis 5 122600
    DISEASE ASSOCIATED WITH tbx16l VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process paraxial mesoderm formation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001699 (1)
  • InterPro:IPR008967 (1)
  • InterPro:IPR018186 (1)
  • InterPro:IPR036960 (1)
  • PROSITE:PS01264 (1)
  • PROSITE:PS01283 (1)
  • PROSITE:PS50252 (1)
  • Pfam:PF00907 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA tbx16l-201 (1) 3080
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM tbx16l
    MARKER RELATIONSHIPS
    tbx16lContained in: [BAC] CH211-207C6 (1) (order this)
    tbx16lEncodes: [EST] cb123 (order this)
    [cDNA] MGC:109816 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131052 (1) 2871bp
    Genomic GenBank:BX548073 (1) 222583bp Blast at MegaBLAST
    Polypeptide UniProtKB:B0S6U6 (1) 488aa
    Sequence Clusters UniGene:224 (1)
    Sequence Information (all 21)
    OTHER tbx16l GENE PAGES
  • Alliance (1)
  • Gene:30254 (1)
  • VEGA:OTTDARG00000018501 (1)
  • Ensembl(GRCz11):ENSDARG00000006939 (1)
  • ORTHOLOGY for tbx16l (Chr: 5)
    CITATIONS (132)