ZFIN ID: ZDB-FIG-110322-31
Pikulkaew et al., 2011 - The knockdown of maternal glucocorticoid receptor mRNA alters embryo development in zebrafish. Developmental dynamics : an official publication of the American Association of Anatomists   240(4):874-889 Full text @ Dev. Dyn.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage Range: Prim-5 to Day 5

Fig. 3

Phenotypes of embryos or larvae at 1, 3, and 5 dpf after treatment with grATG1MO alone or together with MOp53 as compared to control groups (WT or treated with grmismMO or grsplicMO) or after rescuing with t-gr2 mRNA. Fish in Class II are more severely affected than in Class I. Animals are presented as lateral view, anterior to the left. Bar = 500 ┬Ám. The effects of grATG2MO are also shown.

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO2-nr3c1 standard conditions Prim-5 embryo development delayed, abnormal
Prim-5 eye decreased size, abnormal
Prim-5 head decreased size, abnormal
Prim-5 pigmentation delayed, abnormal
Protruding-mouth brain decreased size, abnormal
Protruding-mouth embryo development disrupted, abnormal
Protruding-mouth extension edematous, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth otic vesicle decreased size, abnormal
Protruding-mouth pericardium edematous, abnormal
Day 5 brain decreased size, abnormal
Day 5 embryo development disrupted, abnormal
Day 5 extension edematous, abnormal
Day 5 eye decreased size, abnormal
Day 5 otic vesicle decreased size, abnormal
Day 5 pericardium edematous, abnormal
WT + MO3-nr3c1 standard conditions Prim-5 embryo development delayed, abnormal
Prim-5 eye decreased size, abnormal
Prim-5 head decreased size, abnormal
Prim-5 pigmentation delayed, abnormal
Protruding-mouth brain decreased size, abnormal
Protruding-mouth embryo development disrupted, abnormal
Protruding-mouth extension edematous, abnormal
Protruding-mouth eye decreased size, abnormal
Protruding-mouth otic vesicle decreased size, abnormal
Protruding-mouth pericardium edematous, abnormal
Day 5 brain decreased size, abnormal
Day 5 embryo development disrupted, abnormal
Day 5 extension edematous, abnormal
Day 5 eye decreased size, abnormal
Day 5 otic vesicle decreased size, abnormal
Day 5 pericardium edematous, abnormal
Acknowledgments:
ZFIN wishes to thank the journal Developmental dynamics : an official publication of the American Association of Anatomists for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ Dev. Dyn.