FIGURE

Fig. 1

ID

ZDB-FIG-101101-1

Publication

Ablooglu et al., 2010 - Integrin alphaV is necessary for gastrulation movements that regulate vertebrate body asymmetry

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Fig. 1

Integrin αV knockdown perturbs proper heart tube asymmetry in zebrafish embryos. (A-D) Dorsal views of 28 hours post-fertilization (hpf) embryos hybridized with a probe to cmlc2 to determine heart tube location. Scale bars: 100 μm. (A) Embryo injected with standard control MO. (B-D) Embryos injected with αV1. (E) Bar graphs showing effects of αV integrin loss of function on heart tube location. Data expressed as number of embryos with cmlc2 expression location divided by total number of embryos used per experiment x 100 (%) ± s.e.m. See also Table S1 in the supplementary material.

Expression Data

Gene:	myl7
Fish:	WT WT + MO1-itgav
Knockdown Reagent:	MO1-itgav
Anatomical Term:	heart tube
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT + MO1-itgav
Knockdown Reagent:	MO1-itgav
Observed In:	determination of heart left/right asymmetry heart tube
Stage:	Prim-5

Phenotype Detail

Acknowledgments

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