Fig. S2
- ID
- ZDB-FIG-101101-10
- Publication
- Ablooglu et al., 2010 - Integrin alphaV is necessary for gastrulation movements that regulate vertebrate body asymmetry
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Visceral organ asymmetry in αV morphants can be partially rescued by overexpression of mαV mRNA. (A-H) Dorsal views of standard control MO-injected embryos (A,D,G) and αV1-injected embryos (B,E,H). (A-C) spaw expression in lateral plate mesoderm (LPM; black arrowhead) determined at 15-17 SS. (D-F) lft2 expression in heart primordia (asterisk) at 24 hours post-fertilization (hpf). (G-J) vtn in liver primordia (white arrow) and pdx-1 in pancreatic bud (white arrowhead) at 54-60 hpf. Black arrows in panels D and E show midline marker ntl expression in the notochord. Scale bars: 100 μm. Bar graphs C, F, I and J summarize the effects of αV integrin loss-of-function on localization of spaw in LPM (C), lft2 in heart primordia (F), vtn in liver primordia (I) and pdx1 in the pancreatic bud (J). Data expressed are similar to those from Fig. 1E. See also Table S2 in the supplementary material. |