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Fig. 1 Integrin αV knockdown perturbs proper heart tube asymmetry in zebrafish embryos. (A-D) Dorsal views of 28 hours post-fertilization (hpf) embryos hybridized with a probe to cmlc2 to determine heart tube location. Scale bars: 100 μm. (A) Embryo injected with standard control MO. (B-D) Embryos injected with αV1. (E) Bar graphs showing effects of αV integrin loss of function on heart tube location. Data expressed as number of embryos with cmlc2 expression location divided by total number of embryos used per experiment x 100 (%) ± s.e.m. See also Table S1 in the supplementary material.
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