Fig. 4
- ID
- ZDB-FIG-100616-116
- Publication
- Yao et al., 2010 - Atoh8, a bHLH transcription factor, is required for the development of retina and skeletal muscle in zebrafish
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Phenotypes of translation blocking morpholino (MO1) knockdown embryos. (A?B)13-somite stage. (C?E) 24 hpf. (F?H) 48 hpf. (I?J) 72 hpf. (K?N) somite of mylz2-GFP transgenic zebrafish embryos at 48 hpf. (O?P) mylz2-GFP transgenic zebrafish embryos at 7dpf. A, C?D, F?G, I, K, M and O are Atoh8-MO treated embryos: A, C and F show severe abnormality, D, G, I, K, M and O show mild abnormality, and B, E, H, J, L, N and P are control-MO treated embryos. Atoh8-MO-treated embryos show shrunken eyes and head, a curved body axis with indistinct somite boundaries and yolk extension, accompanied by a U-shaped somite formation. In addition, the branchial arches are greatly reduced(O?P). In all panels but P, the dorsal view is up and the anterior is to the left. P shows the ventral view and the anterior to the left. Abbreviations: re, retina; sm, somite; ba, branchial arches. |
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| Stage Range: | Long-pec to Days 7-13 |
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| Observed In: | (all 10) |
| Stage Range: | 10-13 somites to Protruding-mouth |