FIGURE

Fig. 6

ID

ZDB-FIG-100427-30

Publication

Binot et al., 2010 - Nkx6.1 and nkx6.2 regulate alpha- and beta-cell formation in zebrafish by acting on pancreatic endocrine progenitor cells

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Fig. 6

nkx6.1 and nkx6.2 do not regulate each other. A?D: WISHs showing expression of nkx6.2 in control (A) and nkx6.1 (B) morphants, and of nkx6.1 in control (C) and nkx6.2 (D) morphants. E?G: Double fluorescent WISHs showing expression of nkx6.1 and nkx6.2 in control (E), nkx6.1 (F), and nkx6.2 (G) morphants; Z-plane confocal images. The presented data are representative from at least three reproducible and independent experiments. All views are lateral views of 24 hpf embryos with anterior part to the left. Scale: 20 μm.

Expression Data

Genes:	nkx6.1 nkx6.2
Fish:	AB AB + MO1-nkx6.1 + MO2-nkx6.1 AB + MO3-nkx6.2 + MO4-nkx6.2
Knockdown Reagents:	MO1-nkx6.1 MO2-nkx6.1 MO3-nkx6.2 MO4-nkx6.2
Anatomical Terms:	pancreatic bud ventral side posterior pancreatic bud
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 340(2), Binot, A.C., Manfroid, I., Flasse, L., Winandy, M., Motte, P., Martial, J.A., Peers, B., and Voz, M.L., Nkx6.1 and nkx6.2 regulate alpha- and beta-cell formation in zebrafish by acting on pancreatic endocrine progenitor cells, 397-407, Copyright (2010) with permission from Elsevier. Full text @ Dev. Biol.