FIGURE

Fig. 6

ID

ZDB-FIG-100211-25

Publication

Kok et al., 2010 - Churchill and Sip1a repress fibroblast growth factor signaling during zebrafish somitogenesis

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Fig. 6

Repression of fibroblast growth factor-8 (FGF8) by ChCh is not limited to the mesoderm. A-F: Whole-mount RNA in situ hybridization of pax2a and krox20 in 10-somite stage ChCh and Sip1a compromised embryos. All views are dorsal; anterior to the top. A-C: FGF target gene pax2a is expanded anteriorly in the isthmus in chch morphants, but not in sip1a morphants. D-F: The anterior extent of krox20 expression is not altered by chch or sip1a knockdown. Arrows denote isthmus.

Expression Data

Genes:	egr2b pax2a
Fish:	WT WT + MO2-churc1 WT + MO4-zeb2a
Knockdown Reagents:	MO2-churc1 MO4-zeb2a
Anatomical Terms:	midbrain hindbrain boundary neural rod rhombomere 3 rhombomere 5
Stage:	10-13 somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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