Fig. 3

Transverse sections of mutant retinae at 3 dpf. The phenotypes of (A) oko meduzy (ome)^m98, (B) glass onion (glo)^m117 and (C) nagie oko (nok)^m227 mutants are similar to each other. In the retinae of these mutants the plexiform matter forms patches instead of laminae. ome^m98 and nok^m227 form a well differentiated optic nerves (arrowhead in A). (D) Retina of heart and soul (has)^m129 mutant at 60 hpf. Although the optic nerve is present, the retina of has^m129 does not develop stratification. (E) one eyed pinhead (oep)^m134, (F) cyclops (cyc)^b16 and (G) bozozok (boz)^m168 develop cyclopia. In these mutants retinal stratification develops to a limited degree. Abnormalities of the neuronal patterning are usually associated with presence of numerous cell corpses. (H) Some pandora (pan)^m313 mutants develop normal neuronal lamination. The portion of the retina ventral to the optic nerve (arrowhead in H) is absent in pan^m313. In all panels ventral is down.