FIGURE

Fig. 9

ID

ZDB-FIG-090817-17

Publication

McMahon et al., 2009 - Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish

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Fig. 9

Fgf signaling is activated in lmx1b morphant ocular regions. Whole mount in situ hybridization for fgf3 (A?D) and fgf8 (E?H) in control and lmx1bdMO embryos showing head (A, B, E, F) and higher magnification of the eyes (C, D, G, H). Note the expansion of fgf3 and fgf8 in optic stalk and ventral retinal tissues of lmx1bdMO embryos (solid arrows in panels B, F). In contrast, midbrain?hindbrain expression was decreased in lmx1bdMO morphant embryos (open arrows in panels B, F).

Expression Data

Genes:	fgf3 fgf8a
Fish:	WT WT + MO2-lmx1bb + MO3-lmx1ba
Knockdown Reagents:	MO2-lmx1bb MO3-lmx1ba
Anatomical Terms:	midbrain hindbrain boundary optic cup optic stalk telencephalon
Stage:	Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 332(2), McMahon, C., Gestri, G., Wilson, S.W., and Link, B.A., Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish, 287-298, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.