FIGURE

Fig. 9

ID

ZDB-FIG-090304-52

Publication

Martin et al., 2009 - Plakoglobin has both structural and signalling roles in zebrafish development

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Fig. 9

Loss of plakoglobin results in fewer adhesion junctions and with an altered structure. (A and B) Electron microscopy of the intercalated discs of zebrafish embryo hearts at 72 hpf. (A) In control morpholino injected embryos, desmosomes (black arrowheads) were in series. (B) In morphant embryos, diffuse adhesion junctions (white arrowhead) were detected. (C) A table of indicating the cell–cell borders numbers, the number of adhesion junctions, and the number of each type of junction in control and morphant embryos. Unclassified indicates adhesion junctions that could not be definitively classed as adherens junction, desmosome or tight junction. N = 2 embryos per sample. Scale bar is 100 nm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB + MO1-jupa
Knockdown Reagent:	MO1-jupa
Observed In:	heart adherens junction heart cell-cell junction heart desmosome
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 327(1), Martin, E.D., Moriarty, M.A., Byrnes, L., and Grealy, M., Plakoglobin has both structural and signalling roles in zebrafish development, 83-96, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.