FIGURE

Fig. 3

ID

ZDB-FIG-090113-11

Publication

Esterberg et al., 2009 - dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity

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Fig. 3

cv2 expression is lost from the PPR, otic placode, and pharyngeal arches in Dlx3b/4b morphants. (A,B) cv2 (purple) is co-expressed with dlx3b (red) in the ectoderm of the PPR. Transverse sections were taken through the neural plate of 3-somite embryos. (C,D) Prior to the onset of dlx3b/4b expression, cv2 expression is unaffected on the ventral side of 60% epiboly embryos. (E,F) cv2 expression is lost from the PPR in Dlx3b/4b morphants (F). (G,H) cv2 expression is lost from the otic placode in 18 somite Dlx3b/4b morphants (H). (I,J) cv2 expression is lost from the otic vesicle and pharyngeal arches in 30 hpf (hours post fertilization) embryos (J). ov, otic vesicle; pa, pharyngeal arches. All views are lateral except (E,F), which are dorsal views.

Expression Data

Genes:	bmper dlx3b
Fish:	WT WT + MO5-dlx3b + MO5-dlx4b
Knockdown Reagents:	MO5-dlx3b MO5-dlx4b
Anatomical Terms:	ectoderm lateral mesoderm otic placode otic vesicle pharyngeal arch presumptive ectoderm
Stage Range:	Germ-ring to Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 325(1), Esterberg, R., and Fritz, A., dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity, 189-199, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.