Fig. S2
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- ZDB-FIG-090113-18
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- Esterberg et al., 2009 - dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity
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chd expression is reduced in Dlx3b/4b morphants, but can be rescued when cv2 is ectopically expressed. (A,B,E,F,I,J) chd expression is reduced in Dlx3b/4b morphants (B,F,J). At bud stage, chd expression is reduced in the anterior neural plate (B). At 6 somites, chd expression is reduced in the paraxial mesoderm (F) as well as rhombomeres 3 and 5 (J). (C,G,K) chd expression can be rescued when cv2 is ectopically expressed in Dlx3b/4b morphants. (D,H,L) Expression of the dominant negative form of cv2, cv2-N, causes a reduction of chd expression similar to Dlx3b/4b morphants. (A–D) Bud stage embryos. Dorsal views, with anterior to the top. (E–L) 6 somite stage embryos. (E–H) Caudal views, with dorsal to the top. (I–L) Lateral views, with anterior to the left. |
Reprinted from Developmental Biology, 325(1), Esterberg, R., and Fritz, A., dlx3b/4b are required for the formation of the preplacodal region and otic placode through local modulation of BMP activity, 189-199, Copyright (2009) with permission from Elsevier. Full text @ Dev. Biol.