ZFIN ID: ZDB-FIG-080826-5
Heanue et al., 2008 - Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species. Mechanisms of Development   125(8):687-699 Full text @ Mech. Dev.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Anatomical Terms:
Stage Range: Prim-25 to Pec-fin

Fig. 5 Orthologous zebrafish genes are expressed within the ENS and display similar profiles of expression to their mouse counterparts. Analysis of expression of ret (A–C), nadl1.1 (D–F), nadl1.2 (G–I), dpysl3 (J–L), and fgf13l (M–O), within enteric precursors and their derivatives at 40hpf lateral views (A, D, G, J and M) or dorsal views (B, E, H, K and N) and 60hpf lateral views (C, F, I, L and O). Like ret, nadl1.2 is expressed in migratory enteric precursors at earliest stages, as neural crest migrate in two streams towards the centrally located developing gut tube (arrows in A, B, G, H), and persists as enteric neurons are colonizing the gut tube (distal extent of expression within gut tube marked by arrow in C, I, and individual enteric neurons shown in higher magnification in insets Ci and Ii). In contrast, dpysl3, fgf13l, and nadl1.1 are not expressed in early migratory enteric precursors, but are expressed within enteric neurons colonizing the gut tube (see arrows marking distal extent of expression within gut tube in F, L, O, and marking individual enteric neurons in insets Fi, Li, and Oi). Images for comparison are photographed at the same magnification.

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
dpysl3 WT control Prim-25 Not Detected presumptive enteric nervous system ISH
Pec-fin enteric neuron ISH
fgf13b WT control Prim-25 Not Detected presumptive enteric nervous system ISH
Pec-fin enteric neuron ISH
l1cama WT control Prim-25 presumptive enteric nervous system ISH
Pec-fin enteric nervous system ISH
Pec-fin enteric neuron ISH
l1camb WT control Prim-25 Not Detected presumptive enteric nervous system ISH
Pec-fin enteric neuron ISH
ret WT control Prim-25 presumptive enteric nervous system ISH
Pec-fin enteric nervous system ISH
Pec-fin enteric neuron ISH
Antibody Labeling Details No data available
Phenotype Details No data available
Acknowledgments:
ZFIN wishes to thank the journal Mechanisms of Development for permission to reproduce figures from this article. Please note that this material may be protected by copyright.

Reprinted from Mechanisms of Development, 125(8), Heanue, T.A., and Pachnis, V., Ret isoform function and marker gene expression in the enteric nervous system is conserved across diverse vertebrate species, 687-699, Copyright (2008) with permission from Elsevier. Full text @ Mech. Dev.