Gene

fgf13b

ID

ZDB-GENE-040426-1793

Name

fibroblast growth factor 13b

Symbol

fgf13b Nomenclature History

Previous Names

fgf13l
zgc:76868

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable sodium channel regulator activity. Predicted to be involved in neurogenesis. Predicted to act upstream of or within nervous system development. Predicted to be located in several cellular components, including filopodium; growth cone; and sarcolemma. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including blood; nervous system; neural rod; segmental plate; and trigeminal placode. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 90 and non-syndromic X-linked intellectual disability. Orthologous to human FGF13 (fibroblast growth factor 13).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:76868 (20 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fgf13b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
developmental and epileptic encephalopathy 90	Alliance	Developmental and epileptic encephalopathy 90	301058
		Intellectual developmental disorder, X-linked 110	301095

Associated With fgf13b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR002209	Fibroblast growth factor family
Homologous_superfamily	IPR008996	Cytokine IL1/FGF

Domain Details Per Protein

Protein	Length	Cytokine IL1/FGF	Fibroblast growth factor family
UniProtKB:F6NSV0 InterPro	257
UniProtKB:Q6NZS6 InterPro	193
UniProtKB:A0A0R4IGU4 InterPro	200

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fgf13b-201 (1) Ensembl	Ensembl	2,357 nt	Select Tool ZFIN BLAST
mRNA	fgf13b-203 (1) Ensembl	Ensembl	1,785 nt	Select Tool ZFIN BLAST
mRNA	fgf13b-204 (1) Ensembl	Ensembl	2,475 nt	Select Tool ZFIN BLAST
mRNA	fgf13b-205 (1) Ensembl	Ensembl	2,686 nt	Select Tool ZFIN BLAST
mRNA	fgf13b-206 (1) Ensembl	Ensembl	2,762 nt	Select Tool ZFIN BLAST
ncRNA	fgf13b-002 (1) Ensembl	Ensembl	325 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations