FIGURE

Fig. S3

ID

ZDB-FIG-080604-78

Publication

Peri et al., 2008 - Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo

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Fig. S3

Analysis of apoptosis in wild-type and morphant embryos
A-L Dorsal view of 3-days old zebrafish brains. A-C AnnexinV-Cy5 staining (B) in a APO-GFP (A) wild-type embryo. D-F AnnexinV-Cy5 staining (E) in a APO-GFP (D) morphant embryos. In both there is perfect colocalization between Annexin staining and the APO-E-GFP microglia. G-H Acridine Orange staining in wildtype (G) and a1-MO (H) embryos. I-J CaspGlow staining in wild-type (I) and a1- MO (J) embryos. K-L TMR-TUNEL staining in wild-type (K) and a1-MO (L) embryos.

Expression Data

Gene:	EGFP
Fish:	zf147Tg zf147Tg + MO1-atp6v0a1a
Knockdown Reagent:	MO1-atp6v0a1a
Anatomical Term:	microglial cell
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf147Tg + MO1-atp6v0a1a
Knockdown Reagent:	MO1-atp6v0a1a
Observed In:	neuron apoptotic process
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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Reprinted from Cell, 133(5), Peri, F., and Nüsslein-Volhard, C., Live Imaging of Neuronal Degradation by Microglia Reveals a Role for v0-ATPase a1 in Phagosomal Fusion In Vivo, 916-927, Copyright (2008) with permission from Elsevier. Full text @ Cell