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ZIRC
ZFIN ID: ZDB-GENE-980526-87
Gene Name: wingless-type MMTV integration site family, member 5b
Gene Symbol: wnt5b    Nomenclature History

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Previous Names: wnt5, wnt5a, wnt[b] (1), ZfWnt5 (2), Zwnt[b] (1), CHUNP6928, id:ibd5111, pipe tail, pipetail (1), ppt, wu:fk85g06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Exhibits signaling receptor binding activity. Involved in several processes, including animal organ development; convergent extension; and vasculature development. Predicted to localize to the extracellular space. Is expressed in several structures, including central nervous system; fin; germ ring; head; and mesoderm. Orthologous to human WNT5B (Wnt family member 5B).
Genome Resources: Alliance (1),  Gene:30105 (1),  Ensembl(GRCz11):ENSDARG00000102464 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi1780bTg Transgenic Insertion Exon 4 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • hi2735bTg Transgenic Insertion Intron 4 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la015530Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la024747Tg Transgenic Insertion Unknown Unknown DNA
    la029041Tg Transgenic Insertion Unknown Unknown DNA
    sa33385 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45164 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sk13 Point Mutation Unknown Unknown ENU
    ta98 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tc271b Unknown Unknown Unknown ENU
    te1c Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • th278 Point Mutation Unknown Missense ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ti265 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • wnt5b_unspecified Unspecified Unknown Unknown
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-wnt5b N/A 22
    MO2-wnt5b N/A 6
    MO3-wnt5b N/A 2
    MO4-wnt5b N/A 3
    PHENOTYPE
    Data: 73 figures from 32 publications
    Observed in:
    DISEASE ASSOCIATED WITH wnt5b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH wnt5b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process release of sequestered calcium ion into cytosol (more)
    Cellular Component extracellular region (more)
    Molecular Function signaling receptor binding (more)
    GO Terms (all 35)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA wnt5b-201 (1)    Ensembl 2049
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-wnt5b polyclonal Rabbit IHC AnaSpec
    2
    PLASMIDS
    Addgene:zWnt5b
    CONSTRUCTS WITH SEQUENCES FROM wnt5b
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hsp70l:wnt5b-GFP) hsp70l GFPwnt5b Danio rerio 1 8
    MARKER RELATIONSHIPS
    wnt5b Contained in: [BAC] CH73-211C7 (1) (order this), CH211-281K12 (1) (order this), DKEY-85M15 (1) (order this)
    wnt5b Encodes: [EST] eu891 (1), fk85g06, ibd5111 (1) (order this)
    [STS] chunp6928
    [cDNA] MGC:194419 (1) (order this), MGC:194422 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_130937 (1) 1730 bp
    Genomic GenBank:BX649324 (1) 218137 bp Blast at MegaBLAST
    Polypeptide UniProtKB:B3DI33 (1) 363 aa
    Sequence Clusters UniGene:389 (1)
    Sequence Information (all 33)
    ORTHOLOGY for wnt5b ( Chr: 4 )
    CITATIONS (159)