Gene

wnt5b

ID
ZDB-GENE-980526-87
Name
wingless-type MMTV integration site family, member 5b
Symbol
wnt5b Nomenclature History
Previous Names
  • wnt5
  • wnt5a
  • wnt[b] (1)
  • ZfWnt5 (2)
  • Zwnt[b] (1)
  • CHUNP6928
  • id:ibd5111
  • pipe tail
  • pipetail (1)
  • ppt
  • wu:fk85g06
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Enables signaling receptor binding activity. Involved in muscle cell differentiation; positive regulation of convergent extension involved in gastrulation; and positive regulation of non-canonical Wnt signaling pathway. Acts upstream of or within with a positive effect on midbrain-hindbrain boundary morphogenesis. Acts upstream of or within several processes, including animal organ development; convergent extension; and vasculature development. Predicted to be located in extracellular region. Is expressed in several structures, including central nervous system; cranial cartilage; fin; germ ring; and mesoderm. Human ortholog(s) of this gene implicated in autosomal dominant Robinow syndrome 1. Orthologous to several human genes including WNT5B (Wnt family member 5B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
53 figures from 43 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
78 figures from 35 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt5b Human Ortholog
No data available
Associated With wnt5b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Family IPR026537 Wnt-5b protein
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Wnt Wnt-5b protein Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:B3DI33 363
UniProtKB:Q92050 363
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-wnt5b polyclonal Rabbit
  • IHC
AnaSpec
2
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations