Gene

wnt11f2

ID
ZDB-GENE-990603-12
Name
wnt 11, family member 2
Symbol
wnt11f2 Nomenclature History
Previous Names
  • wnt11 (1)
  • cb748 (1)
  • silberblick
  • slb
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Exhibits protein heterodimerization activity. Involved in several processes, including Kupffer's vesicle development; embryonic morphogenesis; and establishment of mitotic spindle orientation. Localizes to plasma membrane. Is expressed in several structures, including EVL; head; mesoderm; musculature system; and tail bud. Orthologous to human WNT11 (Wnt family member 11).
Genome Resources
Note
Once thought to be the ortholog of human WNT11, the relationship of this wnt gene was clarified in Postlethwait et al. 2019. Evolutionary Origin and Nomenclature of Vertebrate Wnt11-Family Genes. Zebrafish 16(5):469-476.
Expression
All Expression Data
44 figures from 30 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
46 figures from 33 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wnt11f2 Human Ortholog
No data available
Associated With wnt11f2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018161 Wnt protein, conserved site
Family IPR005817 Wnt
Homologous_superfamily IPR043158 Wnt, C-terminal domain
Domain Details Per Protein
Protein Length Wnt Wnt, C-terminal domain Wnt protein, conserved site
UniProtKB:B3DH42 353
UniProtKB:A0A0B5JS77 353
UniProtKB:O73864 354
UniProtKB:B8JM95 353
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-wnt11 polyclonal Rabbit
  • IHC
AnaSpec
2
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations