FIGURE

Fig. 8

ID

ZDB-FIG-080416-14

Publication

Huang et al., 2008 - Histamine metabolism influences blood vessel branching in zebrafish reg6 mutants

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Fig. 8

Association of egr-1 expression and the reg6 vessel branching defect. (A) Expression levels of the egr-1 gene in wild-type (wt; black bars) and reg6 (white bars) 3-dpa regenerates. (B, C) Whole-mount in situ hybridization for egr-1 on wild-type (B) and reg6 (C) 3-dpa regenerates showed decreased expression of egr-1 in reg6 fish. Arrows, egr-1 RNA signal. (D) The egr-1 expression in reg6 mutants was upregulated more than 2.5-fold by 1 mM histamine and 10 μM SKF91488 but was downregulated by 300 μM urocanic acid. The expression level was determined by QPCR and normalized by the expression level of the β-actin gene.

Expression Data

Gene:	egr1
Fish:	y1Tg reg6^j21/j21; y1Tg
Condition:	physical alteration: anatomical structure
Anatomical Term:	regenerating fin
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.