ZFIN is now using GRCz12tu for Genomic Data
Gene
egr1
- ID
- ZDB-GENE-980526-320
- Name
- early growth response 1
- Symbol
- egr1 Nomenclature History
- Previous Names
-
- etID309970.14 (1)
- krox-24
- krox24
- wu:fj64b05
- wu:fq25f01
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable several functions, including double-stranded DNA binding activity; promoter-specific chromatin binding activity; and zinc ion binding activity. Involved in retina layer formation. Acts upstream of or within embryonic retina morphogenesis in camera-type eye; embryonic viscerocranium morphogenesis; and glial cell development. Predicted to be located in cytoplasm and nucleus. Is expressed in head; heart; hindbrain neural keel; mesoderm; and nervous system. Human ortholog(s) of this gene implicated in asthma. Orthologous to human EGR1 (early growth response 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 40 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 13 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Early growth response, N-terminal | Early growth response protein 1, C-terminal | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|---|
| UniProtKB:P26632 | InterPro | 511 | ||||
| UniProtKB:B3DKJ7 | InterPro | 511 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers