FIGURE

Fig. 1

ID

ZDB-FIG-080416-7

Publication

Huang et al., 2008 - Histamine metabolism influences blood vessel branching in zebrafish reg6 mutants

Other Figures

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Fig. 1

Normal migration of regenerating endothelial cells in zebrafish reg6 mutants. (A, B) Combined bright field and green fluorescent images of wild-type TG(fli1:EGFP)^y1(A) and reg6;TG(fli1:EGFP)^y1(B) regenerating fins at 2 days post amputation (dpa) showing the distance (designated by white double arrows) that the blood vessel endothelial cells (ECs) have migrated. Yellow arrows, dilated vessels of reg6 mutants. (C-F) In 3-dpa regenerates, wild-type fish have formed normal capillary plexuses (C, yellow arrows in E)., but reg6 fish (D, bright field; F, green fluorescent) have developed numerous swollen vessels (yellow arrows in D and F) resulting in blood cell accumulation (red spots in D). (G, H) Cross-sections of 3-dpa regenerates showing normal regenerating vessels in wild-type (G) and dilated vessels in reg6 fish (H, yellow arrows). Red arrows, amputation plane. Scale bars, 300 μm. (I) Quantitative data of the migration distance of regenerating ECs in wild-type (black bars) and reg6 fish (white bars) at 2 and 3 dpa.

Expression Data

Gene:	EGFP
Fish:	y1Tg reg6^j21/j21; y1Tg
Condition:	physical alteration: anatomical structure
Anatomical Term:	regenerating fin
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	reg6^j21/j21; y1Tg
Condition:	physical alteration: anatomical structure
Observed In:	blood cell fin vasculature
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ BMC Dev. Biol.