FIGURE

Fig. 4

ID
ZDB-FIG-080331-6
Publication
Lee et al., 2008 - Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish
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Fig. 4

Craniofacial abnormalities in OM2 morphants. (A and B) Ventral view of the head shows several defects (n = 170). Arrows point at underdeveloped olfactory pits. Brackets indicate smaller eyes (A and B). Asterisk shows a malformed mouth. C–F Alcian blue staining of 4 dpf morphants shows the severely impaired pharyngeal arch cartilages (n = 27). Arrows in (C) indicate cartilages in developing pharyngeal arches, which appear absent in OM2 morphants. H, hyoid arch; M, mandibular arch. In (E) and (F) the dramatically reduced cartilage in the pharyngeal arch is again apparent (asterisks in F).

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data
Fish:
Knockdown Reagent:
Observed In:
Stage Range: Pec-fin to Day 4

Phenotype Detail
Acknowledgments
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Reprinted from Mechanisms of Development, 125(1-2), Lee, J.A., Anholt, R.R., and Cole, G.J., Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish, 167-181, Copyright (2008) with permission from Elsevier. Full text @ Mech. Dev.