Image
|
Figure Caption
Fig. 4 Craniofacial abnormalities in OM2 morphants. (A and B) Ventral view of the head shows several defects (n = 170). Arrows point at underdeveloped olfactory pits. Brackets indicate smaller eyes (A and B). Asterisk shows a malformed mouth. C–F Alcian blue staining of 4 dpf morphants shows the severely impaired pharyngeal arch cartilages (n = 27). Arrows in (C) indicate cartilages in developing pharyngeal arches, which appear absent in OM2 morphants. H, hyoid arch; M, mandibular arch. In (E) and (F) the dramatically reduced cartilage in the pharyngeal arch is again apparent (asterisks in F).
Figure Data
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Reprinted from Mechanisms of Development, 125(1-2), Lee, J.A., Anholt, R.R., and Cole, G.J., Olfactomedin-2 mediates development of the anterior central nervous system and head structures in zebrafish, 167-181, Copyright (2008) with permission from Elsevier. Full text @ Mech. Dev.