FIGURE

Fig. 4

ID

ZDB-FIG-080211-37

Publication

Lyons et al., 2008 - KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

kbp is required autonomously in neurons for axonal outgrowth. (A,A′) Lateral views of a chimeric larva generated by transplantation of dextran labeled wild-type cells (red) into a kbp^st23 mutant. Wild-type neurons in the PLLg (arrow, A) extend axons along the entire length of the PLL (A′). Arrowheads point to extended PLLn axons and the rightmost arrowhead in A′ represents an axon innervating the most posterior neuromast near the tip of the tail. (B,B′) Lateral views of a chimeric larva generated by transplantation of dextran-labeled wild-type cells (red) into a kbp^st23 mutant. A single wild-type reticulospinal neuron in the hindbrain (arrow, B) extends an axon along the entire length of the spinal cord (B′). Arrowhead indicates the end of the axon near the tip of the tail.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development