ZFIN ID: ZDB-FIG-070911-9
Perner et al., 2007 - The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros. Developmental Biology   309(1):87-96 Full text @ Dev. Biol.
ADDITIONAL FIGURES
PHENOTYPE:
Fish:
Knockdown Reagents:
Observed In:
Stage: Day 6

Fig. S1 Additional wt1a and wt1b morpholinos serve as controls for specificity. Embryos injected either with control morpholino, a morpholino blocking translation of the wt1a mRNA (AUG) or a morpholino targeting the second splice donor site of the wt1b pre-mRNA (Splc2-2) are shown. Note that the phenotypes resemble closely those of embryos, which were injected with a morpholino targeting the first splice donor site of the respective gene (Fig. 1C).

Gene Expression Details No data available
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
AB/TU + MO2-wt1b standard conditions Day 6 pericardium edematous, abnormal
Day 6 whole organism increased curvature, abnormal
AB/TU + MO3-wt1a standard conditions Day 6 pericardium edematous, abnormal
Day 6 yolk edematous, abnormal
Acknowledgments:
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Reprinted from Developmental Biology, 309(1), Perner, B., Englert, C., and Bollig, F., The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros, 87-96, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.