|ZFIN ID: ZDB-FIG-070911-7|
|Stage Range:||Prim-5 to Long-pec|
Fig. 3 Knockdown of wt1a and wt1b leads to different defects during pronephros development. (A) Confocal images of control and wt1 morpholino-injected wt1b::GFP embryos were recorded 24 and 48 h after fertilization and assembled into 3D projections. (B) Formation of kidney cysts (asterisks) in wt1b morpholino-injected embryos 48 h after fertilization was visualized by H&E staining on cross sections. Note that a part of the glomerular filtration unit was still detectable between the cystic structures. nc, notochord; gl, glomerulus; pt, pronephric tubule; pd, pronephric duct.
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Reprinted from Developmental Biology, 309(1), Perner, B., Englert, C., and Bollig, F., The Wilms tumor genes wt1a and wt1b control different steps during formation of the zebrafish pronephros, 87-96, Copyright (2007) with permission from Elsevier. Full text @ Dev. Biol.