FIGURE

Fig. 1

ID

ZDB-FIG-070621-3

Publication

Cheng et al., 2006 - The homeobox gene irx1a is required for the propagation of the neurogenic waves in the zebrafish retina

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Fig. 1

Developmental expression of irx1a in the zebrafish retina. (A–C) Coronal sections of a 48 hpf zebrafish head revealed irx1a expression in the GCL of the retina (A), but no retinal expression of irx1b or irx7 (B,C). (D) irx1a and isl-1 are co-expressed in the GCL at 48 hpf. (E–L) Lateral views of the dissected eyes at 24 hpf (E,I), 28 hpf (F,J), 32 hpf (G,K) and 36 hpf (H,L). Similar to the expression of ath5 (I–L), irx1a expression is initiated in the ventronasal retina adjacent to the choroid fissure (E) and spreads throughout the retina in a wave-like fashion (F–H). Asterisks (*) indicate the position of the choroid fissure.

Expression Data

Genes:	atoh7 irx1a irx1b irx7 isl1a
Fish:	WT
Anatomical Terms:	presumptive neural retina retina retinal ganglion cell
Stage Range:	Prim-5 to Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 123(3), Cheng, C.W., Yan, C.H., Hui, C.C., Strähle, U., and Cheng, S.H., The homeobox gene irx1a is required for the propagation of the neurogenic waves in the zebrafish retina, 252-263, Copyright (2006) with permission from Elsevier. Full text @ Mech. Dev.