Gene

irx1b

ID
ZDB-GENE-010716-1
Name
iroquois homeobox 1b
Symbol
irx1b Nomenclature History
Previous Names
  • iro1 (1)
  • ziro1 (2)
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have sequence-specific DNA binding activity. Involved in hindbrain development. Predicted to localize to nucleus. Is expressed in several structures, including brain; chordo neural hinge; neural plate; neural rod; and peripheral nervous system. Orthologous to human IRX1 (iroquois homeobox 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
29 figures from 19 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Scholpp et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With irx1b Human Ortholog
No data available
Associated With irx1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR003893 Iroquois-class homeodomain protein
Domain IPR008422 KN homeodomain
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain Iroquois-class homeodomain protein KN homeodomain
UniProtKB:Q90YN0 445
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA irx1b-201 (1) Ensembl 1,746 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations