Gene
atoh7
- ID
- ZDB-GENE-000926-1
- Name
- atonal bHLH transcription factor 7
- Symbol
- atoh7 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of neurogenesis; retina layer formation; and swimming behavior. Predicted to localize to nucleus. Is expressed in eye and immature eye. Human ortholog(s) of this gene implicated in persistent hyperplastic primary vitreous. Orthologous to human ATOH7 (atonal bHLH transcription factor 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 77 figures from 58 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 16 figures from 15 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| persistent hyperplastic primary vitreous | Alliance | Persistent hyperplastic primary vitreous, autosomal recessive | 221900 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Helix-loop-helix DNA-binding domain superfamily | Myc-type, basic helix-loop-helix (bHLH) domain |
|---|---|---|---|
|
UniProtKB:Q8AW52
|
134 |
Interactions and Pathways
No data available
Plasmids
No data available