Expression of NC specification genes. A,B: Expression of snail1b in the premigratory NC cells (arrow) of wild-type embryos (A) is localized to the dorso-lateral edge of the neural tube, but it is greatly reduced in mosm188 mutants (B). The expression in the somites is unaltered. The arrowheads in wild-type embryos demarcate the position of the otic vesicle. C,D:Expression of sox9b is greatly reduced in NC progenitors (arrows) in mosm188 mutants (D), while the otic vesicle expression (arrowheads) is unaltered. E,F: Expression of sox10 in premigratory NC cells of wild-type embryos (E) is localized to the dorso-lateral edge of the neural tube (arrow). Sox10 expression is greatly reduced in mosm188 mutants (F), while the otic vesicle expression (arrowheads) is unaltered. G,H: The wild-type pattern (G) of crestin expression in the cranial region is absent in mosm188 mutants (H), but it is only reduced in the trunk. Lateral views in A-F and dorsal flat mounts in G and H, anterior to the left.
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