FIGURE

Fig. 1

ID

ZDB-FIG-061226-26

Publication

Montero-Balaguer et al., 2006 - The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in zebrafish

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Fig. 1

The mother superior (mos^m188) mutation affects zebrafish craniofacial development. A,B: Lateral view of wild-type (A) and mos^m188 (B) live embryos at 4 dpf. In mos^m188 embryos, the Meckel's cartilage is pointing ventrally and the posterior arches are missing (arrowheads point to the anterior and posterior tips of the Meckel's cartilage). The heart (h) develops an edema. C,D: Ventral view of dissected pharyngeal cartilages stained with Alcian blue from wild-type (C) and mos^m188 (D) embryos at 4 dpf. Cartilage elements corresponding to second and posterior arches (marked 1-5) are severely reduced. cb, ceratobranchial; bh, basihyal; ch, ceratohyal; h, heart; hs, hyosymplectic; M, Meckel's cartilage; pq, palatoquadrate.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	foxd3^m188 (AB)
Observed In:	chondrocyte Meckel's cartilage pericardium pharyngeal arch 2 skeleton pharyngeal arch 3-7 skeleton
Stage:	Day 4

Phenotype Detail

Acknowledgments

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