FIGURE

Fig. 9

ID

ZDB-FIG-060809-9

Publication

Mercader et al., 2006 - Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction

Other Figures

All Figure Page

Back to All Figure Page

Fig. 9

Effect of early Fgf inhibitor treatment on erm, prdm1, fgf24 and tbx5 expression. Whole-mount in situ hybridization on 20.5 hpf (23-somite stage) (A,B,E,F,I,J,M,N) and 24 hpf (C,D,G,H,K,L,O,P) control DMSO and SU5402-treated embryos. Probes are as indicated in each panel. (A-D) erm expression is abolished in SU5402-treated embryos. (E-H) prdm1 expression is downregulated in SU5402-treated embryos. (I-L) Upon SU5402 treatment, Fgf24 is still present at 20.5 hpf but becomes strongly reduced at 24 hpf. (M-P) tbx5 expression is not affected at the 23-somite stage (M,N) but is reduced in 24 hpf embryos upon SU5402 treatment (O,P).

Expression Data

Genes:	etv5b fgf24 prdm1a tbx5a
Fish:	WT
Condition:	chemical treatment: SU5402
Anatomical Terms:	pectoral fin bud pectoral fin field
Stage Range:	20-25 somites to Prim-5

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development