FIGURE

Fig. 4

ID

ZDB-FIG-050214-10

Publication

Galloway et al., 2005 - Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos

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Fig. 4

Expression of Gata-Independent Erythroid Genes(A) Embryos were flat-mounted (anterior, left; posterior, right). Expression of biklf (a–d), KIAA0650 (e–h), testhymin (i–l), and kelch repeat-containing protein (m–p) is maintained in ICM precursors of 12 somite gata1, gata2, and g1/g2 morphants. Anterior expression of biklf stains the hatching gland (a–d).(B) ICM expression of biklf (a–d) at 20 hpf and KIAA0650 (e–h) and testhymin (i–l) at 22 hpf was decreased but present in gata1 morphants (b, f, j) and g1/g2 MO-injected embryos (d, h, l) compared to wild-type embryos (a, e, i). gata2 morphants (c, g, k) had decreased numbers of ICM cells expressing biklf, KIAA0650, and testhymin.

Expression Data

Genes:	gata1a glcci1a klf17 krcp smchd1
Fish:	TU TU + MO1-gata1a TU + MO1-gata2a TU + MO1-gata1a + MO1-gata2a
Knockdown Reagents:	MO1-gata1a MO1-gata2a
Anatomical Terms:	hatching gland intermediate cell mass of mesoderm unspecified
Stage Range:	10-13 somites to 26+ somites

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Cell, 8(1), Galloway, J.L., Wingert, R.A., Thisse, C., Thisse, B., and Zon, L.I., Loss of gata1 but not gata2 converts erythropoiesis to myelopoiesis in zebrafish embryos, 109-116, Copyright (2005) with permission from Elsevier. Full text @ Dev. Cell