ZFIN ID: ZDB-GENE-980526-464

Gene Name:kit receptor a
Gene Symbol: kita

Previous Names: c-kit, sparse, spa-1(1) , spa, kit
Keywords and Sequence Similarities: receptor (1) ; tyrosine kinase (1)
Nomenclature History

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GENE EXPRESSION:(current status)

All expression data:	19 figure(s) from 11 publications
Directly submitted expression data:	6 figure(s) (33 images) from Thisse et al., 2008 [cssl:d114]
Wild Type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Adult (90d-730d, breeding adult)
	anterior axial hypoblast, epiphysis ... (all 20)
Curated microarray expression:	GEO  (1)

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MUTANTS AND TARGETED KNOCKDOWNS:

Mutant line(s):   43 genotypes
Allele(s):   b134, b465, b5, j1e1, j1e15 ... (all 27)

Phenotype: (current status)

Data:	39 figures from 10 publications
Observed in:	gut, head, lateral larval melanophore stripe, melanoblast, melanocyte ... (all 13)

Knockdown reagent: MO1-kita (1)

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GENE PRODUCTS:

Gene Ontology

Ontology	GO Term
Biological Process	developmental pigmentation (more)
Cellular Component	integral to membrane (more)
Molecular Function	ATP binding (more)

All GO Terms (20)

Protein Families, Domains and Sites:

InterPro:IPR000719 (1) InterPro:IPR001245 (1) InterPro:IPR001824 (1) InterPro:IPR003598 (1) InterPro:IPR003599 (1) InterPro:IPR007110 (1) InterPro:IPR008266 (1) InterPro:IPR009134 (1) InterPro:IPR011009 (1) InterPro:IPR013098 (1) InterPro:IPR013783 (1) InterPro:IPR016243 (1) InterPro:IPR017441 (1) InterPro:IPR020635 (1) InterPro:IPR020685 (1) InterPro:IPR020730 (1)

PROSITE:PS00107 (1) PROSITE:PS00109 (1) PROSITE:PS00240 (1) PROSITE:PS50011 (1) PROSITE:PS50835 (1)

Pfam:PF07679 (1) Pfam:PF07714 (1)

EC:2.7.10.1 (1)

Gene Product Description

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CONSTRUCTS WITH SEQUENCE FROM kita:

Et(kita:Gal4TA4,UAS:mCherry)

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SEGMENT (CLONE AND PROBE) RELATIONSHIPS:

kita Contained in	[BAC] CH211-176L11 (1)    (order this) [PAC] BUSM1-116L04 (1)    (order this) , BUSM1-205D10    (order this)
kita Encodes	[cDNA] cssl:d114 (1)    (order this) , MGC:193630 (1)    (order this)

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SEQUENCE INFORMATION:

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_131053 (1)	3545 bp	- Select Tool - ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX276114 (1)	134212 bp	- Select Tool - MegaBLAST Ensembl
Polypeptide	UniProtKB:B3DGS5 (1)	981 aa	- Select Tool - ZFIN BLAST Ensembl SIB BLAST
Sequence Clusters	UniGene:81312 (1)
All Sequence Information (17)

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OTHER  kita  GENE / MARKER PAGES:

Entrez Gene:30256 (1)

VEGA:OTTDARG00000004843 (1)

Ensembl(Zv8):ENSDARG00000043317 (1)

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MAPPING INFORMATION:

LG:  20  Details

View Map: Merged  Individual Panels

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ORTHOLOGY:

				Evidence
Species	Symbol	Chromosome (Position)	Accession #	AA	NT	CL
Zebrafish	kita	20
Human	KIT	4 (q11-q12)	OMIM:164920 Entrez Gene:3815
Mouse	Kit	5 (42.00 cM)	MGI:96677 Entrez Gene:16590
Orthology Details

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CITATIONS   (69)