ZFIN ID: ZDB-PUB-961014-1088
Segregation analysis and gene-centromere distances in zebrafish
Streisinger, G., Singer, F., Walker, C., Knauber, D., and Dower, N.
Date: 1986
Source: Genetics   112: 311-319 (Journal)
Registered Authors: Streisinger, George, Walker, Charline
Keywords: none
MeSH Terms:
  • Animals
  • Centromere*
  • Chromosomes*
  • Fishes/genetics*
  • Genetic Linkage*
  • Genetic Markers
  • Homozygote
  • Lod Score
  • Mutation
  • Pigmentation
  • Recombination, Genetic
PubMed: 3455686
The gol-1, gol-2, alb-1 and spa-1 mutations affect pigment pattern in the zebrafish. We show here that these loci are unlinked to each other. In addition, gene-centromere distances were determined for these loci by analysis of half- tetrads obtained by the inhibition of the second meiotic division. The fractions of tetratype (second-division segregation) tetrads range from 0.24 (spa-1) to 0.89 (gol-1). The observation of greater than 0.67 second-division segregation indicates that the zebrafish has high chiasma interference.