Gene
rbmx
- ID
- ZDB-GENE-030131-579
- Name
- RNA binding motif protein X-linked
- Symbol
- rbmx Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have chromatin binding activity and nucleic acid binding activity. Predicted to be involved in several processes, including RNA metabolic process; cellular response to interleukin-1; and regulation of mRNA splicing, via spliceosome. Predicted to localize to extracellular exosome and nucleus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Shashi type. Is expressed in several structures, including brain; digestive system; immature eye; notochord; and retinal ganglion cell layer. Orthologous to several human genes including RBMX (RNA binding motif protein X-linked).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 12 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:56625 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
syndromic X-linked intellectual disability Shashi type | Alliance | ?Intellectual developmental disorder, X-linked syndromic, Shashi type | 300238 |
X-linked mental retardation Gustavson type | Alliance | ?Intellectual developmental disorder, X-linked syndromic, Gustavson type | 309555 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain | RNA recognition motif domain, eukaryote |
---|---|---|---|---|---|
UniProtKB:Q7ZWA3
|
379 | ||||
UniProtKB:A0A8M6Z2K5
|
374 | ||||
UniProtKB:A0A8M9QP18
|
379 | ||||
UniProtKB:A0A8M9QKH0
|
277 |
Interactions and Pathways
No data available
Plasmids
No data available