Gene
gapdh
- ID
- ZDB-GENE-030115-1
- Name
- glyceraldehyde-3-phosphate dehydrogenase
- Symbol
- gapdh Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; microtubule binding activity; and peptidyl-cysteine S-nitrosylase activity. Predicted to be involved in several processes, including glycolytic process; peptidyl-cysteine S-trans-nitrosylation; and protein stabilization. Predicted to localize to cytosol; microtubule cytoskeleton; and nucleus. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including cardiovascular system; integument; musculature system; nervous system; and pleuroperitoneal region. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 43 figures from 31 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb609 (28 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Active_site | IPR020830 | Glyceraldehyde 3-phosphate dehydrogenase, active site |
Domain | IPR020828 | Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain |
Domain | IPR020829 | Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain |
Family | IPR006424 | Glyceraldehyde-3-phosphate dehydrogenase, type I |
Family | IPR020831 | Glyceraldehyde/Erythrose phosphate dehydrogenase family |
Homologous_superfamily | IPR036291 | NAD(P)-binding domain superfamily |
Domain Details Per Protein
Protein | Length | Glyceraldehyde 3-phosphate dehydrogenase, active site | Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain | Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain | Glyceraldehyde-3-phosphate dehydrogenase, type I | Glyceraldehyde/Erythrose phosphate dehydrogenase family | NAD(P)-binding domain superfamily |
---|---|---|---|---|---|---|---|
UniProtKB:Q5XJ10
|
333 |
Interactions and Pathways
No data available
Plasmids
No data available