ZFIN ID: ZDB-GENE-030115-1
Gene Name: glyceraldehyde-3-phosphate dehydrogenase
Gene Symbol: gapdh    Nomenclature History

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Previous Names: gapd (1), bb02e05, cb609 (1), mg:bb02e05, wu:fb33a10, wu:ft80f05

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; microtubule binding activity; and peptidyl-cysteine S-nitrosylase activity. Predicted to be involved in several processes, including glycolytic process; peptidyl-cysteine S-trans-nitrosylation; and protein stabilization. Predicted to localize to cytosol; microtubule cytoskeleton; and nucleus. Is expressed in several structures, including cardiovascular system; integument; musculature system; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Alzheimer's disease. Orthologous to human GAPDH (glyceraldehyde-3-phosphate dehydrogenase).
Genome Resources: Alliance (1),  Gene:317743 (1),  Ensembl(GRCz11):ENSDARG00000043457 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6419 Point Mutation Unknown Premature Stop ENU
sa42694 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gapdh HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH gapdh VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process microtubule cytoskeleton organization (more)
    Cellular Component cytosol (more)
    Molecular Function glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gapdh-201 (1)    Ensembl 1331
    gapdh-202 (1)    Ensembl 445
    gapdh-203 (1)    Ensembl 825
    gapdh-204 (1)    Ensembl 902
    ncRNA gapdh-005 (1)    Ensembl 834
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab6-gapdh polyclonal Rabbit GeneTex
    2
    Ab1-gapdh monoclonal Mouse WB Abcam plc
    1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gapdh No data available
    MARKER RELATIONSHIPS
    gapdh Contained in: [BAC] DKEY-260G12 (1) (order this)
    gapdh Encodes: [EST] bb02e05, cb609 (1) (order this), fb33a10 (1), ft80f05
    [cDNA] MGC:86789 (1), MGC:110724 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001115114 (1) 1329 nt
    Genomic GenBank:CU861451 (1) 120950 nt
    Select Tool
    Polypeptide UniProtKB:Q5XJ10 (1) 333 aa
    Sequence Information (all 25)
    ORTHOLOGY for gapdh ( Chr: 16 )
    CITATIONS (426)